There is growing evidence that oxidative stress and inflammation are associated with the risk of heart disease (1). Oxidation of low-density lipoproteins (LDL, bad cholesterol) has been linked to increase in the formation of plaques in blood vessels (2). Astaxanthin has been shown to reduce oxidation of LDL (3) and reduce LDL and oxidative stress in a human trial of overweight individuals (4). Animal studies also showed that astaxanthin may support a delayed progression in high-risk stroke cases (5). It has also been shown clinically that astaxanthin reduces C-reactive protein, which is a biomarker for inflammation and associated with a greater risk of developing heart disease (6).
- Pashkow, FJ. Oxidative Stress and Inflammation in Heart Disease: Do Antioxidants Have a Role in Treatment and/or Prevention? Int J Inflam. (2011) 9 pages. REF
- Sarwar et al. Triglycerides and the Risk of Coronary Heart Disease. Circulation. (2007) 115:450-458. REF
- Iwamoto et al. Inhibition of Low-Density Lipoprotein Oxidation by Astaxanthin. (2000) 7: 216-222. REF
- Choi et al. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. (2011) 66:363-9. REF
- Shen et al. Astaxanthin reduces ischemic brain injury in adult rats. FASEB J. (2009) 23: 1958–1968. REF
- Park et al. Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans. Nutrition & Metabolism (2010) 7: 10 pages. REF